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LeanBiome Review: Will It Help You Reach Your Dream Weight?

LeanBiome uses probiotic science to help rebalance gut bacteria, reduce fat storage, and support sustainable weight loss and digestive health.
By The Diet Insiders Staff Updated: 2025, Jul 21 Fact Check Reviewed by a Team of Medical and Nutritional Professionals
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2025-07-22T16:14:03+00:00

Overview

If you’re looking for the optimal all-natural weight loss supplement to boost your slimming efforts, LeanBiome may be the right solution for you. This doctor-formulated blend promotes fat and weight loss, curbs hunger, and optimizes digestion without the use of stimulants. Let’s get into the details of LeanBiome natural weight loss supplement.

What is LeanBiome?

LeanBiome is an organic, plant-based weight loss supplement that works by balancing the gut microbiome and speeding up the metabolism naturally, without stimulants.

The potent bioactive formula is rich in probiotics, prebiotics, polyphenols, and other organics that improve digestion, boost energy, curb hunger and cravings, strengthen the immune system, and lower cholesterol and blood sugar.

According to a research review published in Gut Microbes by Dimitrios A. Koutoukidis, “Increasing weight loss is positively associated with increases in gut microbiota α-diversity and reductions in intestinal permeability [1].

The LeanBiome supplement is vegan-friendly, free of common allergens like nuts, dairy, gluten, sugar, and crustaceans, and has no serious potential side effects. Will it get you to your goal weight faster?

In this review, we’ll get into the details and answer all of your questions about LeanBiome. Keep reading to find out if it’s the best natural slimming formula for you!

LeanBiome
Editor’s Rating
4.7 / 5.0
Overall Rating

LeanBiome

Summary

  • Contains 100% organic ingredients
  • Doctor-formulated
  • Suitable for vegetarian and vegan diets
  • Free of BPAs, GMOs, stimulants, nuts, dairy, gluten, sugar, and crustaceans
  • 180-day 100% money-back guarantee

Official Website*All the prices mentioned on their websites are subject to change.

ingredient

4.6/ 5

Ingredients

value-for-cost

4.5 / 5

value for cost

effectiviness

4.7 / 5

effectiveness

safety

4.5 / 5

safety

Specification Insight

manufacturemanufacture LeanBiome by Lean for Good®
made-inmade in USA
typetype Weight loss supplement
Amount per BottleAmount per Bottle 60 capsules
DosageDosage 2 capsules daily
main-benefitsmain benefits Promotes fat and weight loss, curbs hunger and cravings, balances the gut microbiome, improves digestion, increases energy, lowers cholesterol and blood sugar, strengthens the immune system
key-ingredientkey ingredient Garcinia Mangostana, Green Tea Phytosome (decaffeinated), Sphaeranthus Indicus, Lactobacillus Gasseri, Bifidobacterium Lactis, Lactobacillus Rhamnoses, Lactobacillus Plantarum, Bifidobacterium Breve, Bifidobacterium Longum, Lactobacillus Fermentum, Lactobacillus Paracasei, Inulin from Chicory Root
allergen-warningallergen warning Free of nuts, dairy, gluten, sugar, and crustaceans, vegan-friendly
safety-informationsafety information Manufactured in the USA in an FDA-registered, GMP-certified facility
priceprice
  • 1 Bottle – $59
  • 3 Bottles – $49/each
  • 6 Bottles – $39/each

Who is the Manufacturer?

The supplement manufacturer is a company called Lean for Good® headquartered in Nashville, Tennessee. They have offices worldwide, and their focus is on producing all-natural, doctor-formulated supplements for weight loss. Nashville, Texas. LeanBiome is their flagship product.

How Does It Work?

LeanBiome contains several key probiotic strains. As we said in our review of Roundhouse Morning Kick, these are healthy bacteria that live in the intestines eliminating managing microbes and balancing to microbiome.

A research review published in the Journal of Microbiology and Biotechnology by Seon-Kyun Kim, et al discussed the role of probiotics in ameliorating diseases associated with the gut microbiome [2].

The LeanBiome supplement is high in prebiotic fiber that feeds the probiotics in the gut so they can proliferate and promote optimal digestion. This helps cleanse the colon, promote healthy bowel movements, and ease issues like cramping, bloating, and constipation.

In addition, as we said in our review of Trimtone, fiber slows the digestive process to keep you feeling satiated for longer, so you take in fewer daily calories

A review article by Ruhee Ruheea Taskin, et al published in Advances in Medical Research found strong support for the benefits of daily fiber intake in reducing the prevalence of obesity [3].

There are potent anti-inflammatory agents in LeanBiome that lower swelling in the body, supporting the health of many organs and systems like the heart, digestive tract, liver, brain, and kidneys.

LeanBiome has powerful antioxidants like polyphenols that lower oxidative stress by killing free radicals, for a boost to your immune system. They also speed up the metabolism, which leads to natural fat-burning and weight loss.

A review published in the International Journal of Molecular Sciences by Mariarosaria Boccellino and Stefania D’Angelo examined the anti-obesity properties and benefits of dietary polyphenol intake [4].

What Are the Key Ingredients?

These are some of the primary active ingredients in LeanBiome:.

Inulin

Derived from chicory root, inulin is a prebiotic fiber that feeds healthy probiotics in the gut to promote a healthy, balanced microbiome. It improves gut health, and insulin also slows digestion to curb appetite and cravings, regulates lipid metabolism, and lowers blood sugar.

A study of obese mice published in Frontiers in Nutrition by Zeang Wu, et al concluded that inulin promotes weight loss by regulating the gut microbiota [5].

Bifidobacterium Breve

This is a common probiotic strain that lives along the walls of the intestines, destroying harmful bacteria to promote a balanced, healthy microbiome. Additional intake can help promote weight loss, regulate bowel movements, and ease issues like gas and bloating.

A 12-week clinical trial of healthy individuals published in Nutrients by Hyun Kyung Sung, et al concluded that Bifidobacterium Breve helped reduce weight, and waist and hip circumference [6].

Green Tea Phytosome (decaffeinated)

Green tea is rich in polyphenols like ECGC that can increase metabolism speed to initiate the burning of natural fat stores and weight loss. It may also lower cholesterol and blood sugar, decrease stress, reduce inflammation, and strengthen general health and immunity.

A study of obese women published in BMC Complementary Medicine and Therapies by Luisa Gilardini, et al showed that supplementation with green tea helped women to maintain weight they lost during a 3-month diet program [7].

Taste and Aroma

The LeanBiome tablets have acid-resistant coating that has no flavor or scent and they are small and easy to take. They are delayed-release capsules designed to reach your stomach safely before they start to work.

Pros and Cons

Pros

  • LeanBiome can promote fat-burning and weight loss.
  • This supplement can balance the gut microbiome and enhance digestive health.
  • LeanBiome can boost your energy levels.
  • The product can lower cholesterol and blood sugar levels.
  • LeanBiome can suppress appetite and cravings.

Cons

  • You can only purchase LeanBiome online, not in stores.
  • The weight loss results may vary depending on lifestyle and metabolic factors.
  • There are no free samples of the LeanBiome supplement available.

How Does It Compare with Other Brands?

Product Price Active Ingredients Return Policy
PhenQ $69.99 Capsimax, Caffeine, Nopal Cactus, Chromium, L-Carnitine Fumarate 67-Day Money Back Guarantee
Trimtone $59.99 Green Coffee, Green Tea, Glucomannan, Caffeine, Grains of Paradise 100-Day Money Back Guarantee

Overall Appeal

The LeanBiome has great appeal as a natural weight loss supplement when it comes to the purity of the science-backed ingredients, the stimulant, vegan-friendly, allergen-free formula, and the excellent reputation of the manufacturer.

It also provides multiple health benefits in addition to fat and weight loss, including boosting energy levels, lowering blood sugar and cholesterol, and optimizing digestion.

Side Effects

LeanBiome contains a blend of pure organic ingredients that have no serious potential side effects, and the formula is free of GMOs, BPAs, stimulants, nuts, dairy, gluten, sugar, and crustaceans. In addition, the company manufactures safely in an FDA-registered, GMP-certified facility in the USA.

FAQs

Q. Does It Work?

A. While individual results always vary, LeanBiome is a doctor-formulated weight loss supplement with research-baked ingredients, and it should work well for most people to promote weight loss, improve digestion, and offer other health benefits.

Q. What is the Return Policy?

A. Clearly, the manufacturer believes in the quality and efficacy of LeanBiome because they offer an outstanding 180-day 100% money-back guarantee.

If you try it for 6 months and do not get the results you wanted, contact LeanBiome customer service, and send back any remaining sealed bottles within 180 days of the order. You should get a full refund of the purchase price, and you can keep any open bottles.

Q. How Do You Take It?

A. Take 2 capsules with a glass of water once daily. Do not exceed this dosage unless specifically directed by a physician.

Q. Where Can You Buy It?

A. While you can find LeanBiome on Amazon, we highly recommend that you buy from the official website to ensure you are getting the genuine supplement, and to take advantage of their great deals.

The company offers discounts on bulk orders, a bonus product for orders of 3 bottles or more, and free U.S. shipping for orders of 6 bottles or more. This is the price list:

  • 1 Bottle – $59
  • 3 Bottles – $49/each
  • 6 Bottles – $39/each

Q. What Sets It Apart from the Competition?

A. LeanBiome is a doctor-formulated weight loss supplement that works by balancing the gut microbiome and speeding up the metabolism with polyphenols. Unlike many of the competing brands, it does not include stimulants and is also free of many common allergens and additives.

Customer Reviews

LeanBiome is a favorite natural weight loss supplement for us, and we give it a stellar rating of 4.6 out of 5 stars. We love the science-backed, stimulant and allergen-free formula that effectively promotes weight loss and optimizes digestion.

The average customer rating on the official website is 5 stars, and there are several glowing reports from users who lost significant amounts of weight and experienced other health benefits.

One of the top 5-star comments is from Shannon Johnson in California, who loves the benefits of LeanBiome:


I was able to lose 15 lbs and now have more pep in my step! “I have a toddler so I’m constantly looking for something to help boost my energy and to help me lose weight.

And with LeanBiome I’ve actually been able to do just that! I’ve got a little more pep in my step, and I was able to lose close to 15 lbs. It was like 14 point something. I would recommend it for anyone that has kids or a busy schedule that can’t let you work out.

On Amazon, 218 customers give a somewhat lower but still good rating of 3.7 stars. Many of the reviews rave about LeanBiome, and one of the top 5-star reviews is from Mrs. Rosa, who explains:


I saw an ad about this product on Facebook. I decided to try it and purchased it through Amazon. I’ve been taking it for about a week now. It’s helped me so much. No bloating stomach is nice and flat. Have more energy as well.

It’s really helping my digestive system. I’ve had so many digestive issues and have tried so many different products, but this one literally does what it says. Definitely will continue to purchase.

One of the most critical one-star LeanBiome reviews on Amazon comes from susk4, who says the supplement is not worth it:


Followed the instructions and saw no change in weight at all. I included working out and eating healthy.

The Bottom Line

In our view, LeanBiome is a leading all-natural weight loss supplement formulated by physicians with optimal ingredients backed by science. Our rating is a very high 4.6 out of 5 stars, and find it highly effective at optimizing digestion, promoting fat and weight loss, boosting energy, lowering cholesterol and blood sugar, and more.

On the official website, LeanBiome reviews rate the supplement an average of 5 stars and many rave about significant weight loss and digestive health benefits. Amazon users also give a moderately high rating, and many have very positive comments about LeanBiome.

LeanBiome includes a blend of 100% organic ingredients and is free of stimulants, GMOs, BPAs, nuts, dairy, gluten, sugar, and crustaceans. It has no serious potential side effects and is vegan-friendly. The highly reputable manufacturer produces LeanBiome in an FDA-registered, GMP-certified facility in the USA.

Where to Buy LeanBiome?

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References

[1]. The Association of Weight Loss with Changes in the Gut Microbiota Diversity, Composition, and Intestinal Permeability: A Systematic Review and Meta-Analysis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796717/
[2]. Role of Probiotics in Human Gut Microbiome-Associated Diseases: https://www.jmb.or.kr/journal/view.html?doi=10.4014/jmb.1906.06064
[3]. https://www.researchgate.net/publication/330872321_Dietary_Fiber_and_its_Effect_on_Obesity_A_Review_Article
[4]. Anti-Obesity Effects of Polyphenol Intake: Current Status and Future Possibilities: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460589/
[5]. Inulin Accelerates Weight Loss in Obese Mice by Regulating Gut Microbiota and Serum Metabolites: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554005/
[6]. Body Fat Reduction Effect of Bifidobacterium breve B-3: A Randomized, Double-Blind, Placebo Comparative Clinical Trial: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824586/
[7]. Effects of Greenselect Phytosome® on Weight Maintenance After Weight Loss in Obese Women: A Randomized Placebo-Controlled Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957378/
[8]. Increased Dietary Fiber is Associated with Weight Loss Among Full Plate Living Program Participants: https://www.frontiersin.org/articles/10.3389/fnut.2023.1110748/full
[9]. Beneficial Effects of Green Tea: A Literature Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855614/
[10]. Effects of Probiotics and Synbiotics on Weight Loss in Subjects with Overweight or Obesity: A Systematic Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540110/
[11]. Effects of a Diet Based on Inulin-Rich Vegetables on Gut Health and Nutritional Behavior in Healthy Humans: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537941/
[12]. Bifidobacterium Longum: Protection against Inflammatory Bowel Disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324359/

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy. Colon Health Magazine adheres to strict editorial integrity standards. To the best of our knowledge, all content is accurate as of the date posted, though offers contained herein may no longer be available. The opinions expressed are the author's alone and have not been provided, approved or otherwise endorsed by our advertisers.

*Individual Results may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. Your health and wellness is unique to you, and the products and services we review may not be right for your circumstances. The information contained in this website is provided for educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. For personal advice, please consult with a medical professional.

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